The Bess Lab
Discovering & Engineering Microbiome Chemistry
© 2023, The Bess Lab
May 24, 2023
The Chao Family Com- prehensive Cancer Center is supporting the Bess, Jang, and Whiteson Labs to use the gut microbiome to predict effectiveness of anti-cancer drugs.
Jun. 23, 2022
Check out our Article in J. Appl. Microbiol. on an a way that gut bacteria can synthesize dopamine.
Mar. 23, 2021
Congratulations to graduate student Zane Long for being awarded an Honorable Mention for his application to the NSF Graduate Research Fellowship Program!
June 16, 2020
Bess Lab awarded UC Irvine Hellman Fellowship!
Oct. 7, 2022
Thanks to support from the ACS TheoryLab Collaborative Grant for the support, the Bess and Jang Labs are mapping the gut microbiome's role in fighting breast cancer.
Jun. 8, 2022
Check out our pre-print on bioRxiv showing how gut bacteria convert dopamine, iron, and α-synuclein into a toxic trio that causes α-synuclein aggregation and neurodegeneration
Jan. 5, 2021
Congratulations to 3rd-year graduate student Barry Rich for receiving the prestigious ARCS Scholar Award.
Jan. 10, 2020
Professor Bess named a Scialog fellow by Research Corp.
Aug. 24, 2021
Check out our Commentary in mSystems about how C. elegans can be used to dissect the gut–grain axis.
Oct. 1, 2020
Honored to be supported by the UC Cancer Research Coordinating Committee for our research on the gut microbiome's role in breast cancer therapy.
Oct. 10, 2019
Honored to be supported by the American Cancer Society and UCI for our work on estrogen and the gut microbiome.
Jun. 30, 2022
Excited to work with Aida Ebrahimi's lab to study the electro-chemistry of gut bacteria's role in α-synuclein aggregation. Thanks to RSCA for the support!
May. 28, 2021
Congratulations to Kylie Uyeda and Zane Long, the newest PhD candidates in the Bess Lab!
July 31, 2020
Delighted to be supported by the Global Probiotics Council to study the chemical reactions that gut bacteria perform when they degrade fiber.
Jun. 30, 2022
Honored to be supported by RSCA to work with Stephanie Cologna's lab and Faranak Fattahi's lab to study how α-synuclein aggregates form in the enteric nervous system
Mar. 23, 2021
Congratulations to graduate student Kylie Uyeda for being awarded an Honorable Mention for her application to the NSF Graduate Research Fellowship Program!
July 17, 2020
Bess Lab celebrates its first student advancing to PhD candidacy! Congratulations, Barry!
ADME Models
We are characterizing the chemical-reaction repertoire of the gut microbiome—informing drug absorption, distribution, metabolism, and excretion (ADME) models—to uncover the microbiome's impacts on pharmacology and health.
Hormone Signaling
We are elucidating the molecular mechanisms by which the microbiome mediates hormone levels in humans, which has important implications for health and disease.
Gut—Brain Axis
There is mounting evidence that the human gut microbiome impacts the brain. We are unravelling the molecular-level mechanisms causally linking the gut microbiome to Parkinson’s disease pathogenesis.
Dietary Fiber
Lignocellulose is an abundant but understudied dietary fiber. We are discovering how gut bacterial degradation of this dietary fiber shapes the functions and chemical environment of the gut microbiome.