There is mounting evidence that the human gut microbiome impacts the brain. We are unravelling the molecular-level mechanisms that causally link the gut microbiome to Parkinson’s disease pathogenesis.

We are elucidating the molecular mechanisms by which the microbiome mediates hormone levels in humans, which has important implications for health and disease.

Lignin is highly abundant, yet undervalued, biomass. We are developing methods to valorize this renewable resource by building upon the chemical reactions encoded in bacteria.

We are characterizing the chemical-reaction repertoire of the gut microbiome—informing drug absorption, distribution, metabolism, and excretion (ADME) models—to uncover the microbiome's impacts on pharmacology and health.